THE USE OF INTERIM DATA AND DATA MONITORING COMMITTEE RECOMMENDATIONS IN RANDOMIZED CONTROLLED TRIAL REPORTS: FREQUENCY, IMPLICATIONS AND POTENTIAL SOURCES OF BIAS

Abstract Background Interim analysis of accumulating trial data is important to protect participant safety during randomized controlled trials (RCTs).Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial results.Metho

Setup and management of smart home systems is a complex task, and thus challenging for technically inexperienced users.We conducted a qualitative user study to evaluate whether an assistance system could empower users to make better and informed decisions regarding kiara sky peach sangria the selection of devices, their interoperability, the result